Yeast cell-surface expression of chitosanase from Paenibacillus fukuinensis.

نویسندگان

  • Takeshi Fukuda
  • Danya Isogawa
  • Madoka Takagi
  • Michiko Kato-Murai
  • Hisashi Kimoto
  • Hideo Kusaoke
  • Mitsuyoshi Ueda
  • Shin-Ichiro Suye
چکیده

To produce chitoorigosaccharides using chitosan, we attempted to construct Paenibacillus fukuinensis chitosanase-displaying yeast cells as a whole-cell biocatalyst through yeast cell-surface engineering. The localization of the chitosanase on the yeast cell surface was confirmed by immunofluorescence labeling of cells. The chitosanase activity of the constructed yeast was investigated by halo assay and the dinitrosalicylic acid method.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Conversion of Squid Pens to Chitosanases and Proteases via Paenibacillus sp. TKU042

Chitosanases and proteases have received much attention due to their wide range of applications. Four kinds of chitinous materials, squid pens, shrimp heads, demineralized shrimp shells and demineralized crab shells, were used as the sole carbon and nitrogen (C/N) source to produce chitosanases, proteases and α-glucosidase inhibitors (αGI) by four different strains of Paenibacillus. Chitosanase...

متن کامل

Investigation of Paenibacillus larvae subspecies larva of honey bee (Apis mellifera) colonies in East Azerbaijan Province of Iran

Background: The American foulbrood disease (AFB), caused by Paenibacillus larvae subsp. larvae, is one of the main plagues affecting honey bee (Apis mellifera L.) colonies, and it has a high negative impact on beekeepers worldwide. OBJECTIVES: The aim of this research was to describe the evidence of Paenibacillus larvae larvae contamination of honey bee colonies, in the East Azerbaijan Province...

متن کامل

Isolation, Subtype Determination, Cloning and Expression of HBsAg Gene from an Iranian Carrier in Saccharomyces cerevisiae

The Hepatitis B Surface antigen ( HBsAg) gene was isolated from an Iranian HBeAg positive carrier by PCR. The gene was cloned in pUC19 for sequencing and pYES2 for expression in Saccharomyces cerevisiae, which pNF1 and pDF3 constructs were made respectively. The sequencing data showed that the isolated HBsAg gene shared more than 90% homology with the ayw subtype. The pDF3 was transferred into ...

متن کامل

Isolation, characterization and heterologous expression of a novel chitosanase from Janthinobacterium sp. strain 4239

BACKGROUND Chitosanases (EC 3.2.1.132) hydrolyze the polysaccharide chitosan, which is composed of partially acetylated beta-(1,4)-linked glucosamine residues. In nature, chitosanases are produced by a number of Gram-positive and Gram-negative bacteria, as well as by fungi, probably with the primary role of degrading chitosan from fungal and yeast cell walls for carbon metabolism. Chitosanases ...

متن کامل

Single Cell Oil Production from Petroleum Sludge by Native Yeast Strains

In this research, 11 yeast strains with ability to grow on petroleum sludge were isolated from effluent of a petroleum refinery. Based on growth on mineral media contaminated petroleum sludge, two isolates were selected as the super strains. Meanwhile, results based on biochemical and morphological experiments on the strains indicated that the two selected isolates belonged to Candida and Proto...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Bioscience, biotechnology, and biochemistry

دوره 71 11  شماره 

صفحات  -

تاریخ انتشار 2007